Vitamin D plays a critical role in immune system regulation, making it a key factor in managing autoimmune diseases. This essential nutrient supports immune tolerance, helping prevent the immune system from attacking the body’s own tissues. Low levels of vitamin D have been associated with a higher risk of autoimmune conditions such as multiple sclerosis, rheumatoid arthritis, and lupus. Studies suggest that vitamin D supplementation may reduce inflammation and improve immune function in individuals with autoimmune diseases, though more research is needed to determine optimal levels for therapeutic effects.
The Implication of Vitamin D and Autoimmunity: a Comprehensive Review
Conclusion
“Vitamin D, in addition to its crucial role in bone metabolism, has been associated with multiple autoimmune diseases in several epidemiological studies. Due to its unique capability to bind to VDR and serve as a transcriptional factor, vitamin D can regulate gene expression and further exert its immunomodulatory effects on immune cells.”
